Directed by Ron Howard, A Beautiful Mind (2001) stars Russell Crowe as mathematician John Nash, a brilliant scholar whose groundbreaking work in game theory is overshadowed by his struggle with mental illness. Jennifer Connelly co-stars as his wife Alicia Nash. The film won four Academy Awards including Best Picture and Best Director.

Från IMDB:
A mathematical genius, John Nash made an astonishing discovery early in his career and stood on the brink of international acclaim. But the handsome and arrogant Nash soon found himself on a harrowing journey of self-discovery.