David Cronenberg’s The Fly (1986) is a landmark body horror classic, starring Jeff Goldblum as a scientist whose teleportation experiment mutates him into a grotesque hybrid of man and insect. Mixing romance, tragedy, and visceral horror, the film became a critical and commercial hit, cementing Cronenberg’s reputation as the master of transformation and terror.

Från IMDB:
A brilliant but eccentric scientist begins to transform into a giant man/fly hybrid after one of his experiments goes horribly wrong.