Directed by Robert Harmon, The Hitcher stars C. Thomas Howell as a young driver whose journey across the American Southwest becomes a nightmare after he picks up a mysterious hitchhiker played by Rutger Hauer. Jennifer Jason Leigh co-stars in this road thriller and horror film built around pursuit, psychological intimidation and a seemingly unstoppable killer.

A would-be samaritan picks up a hitchhiker and soon discovers the man is a relentless serial killer. Framed by the cold-blooded murderer for a string of slayings, his only help comes from a caring waitress as they attempt to flee from both the law and the hitcher.

Från IMDB:
A young man who escapes the clutches of a murderous hitchhiker is subsequently stalked by the hitcher and framed for his crimes.